Hormone Therapy and Cardiovascular Disease

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Hormone replacement therapy and cardiovascular disease.

Oestrogen alone probably confers a degree of protection against ischaemic heart disease and stroke and is appropriate for women requiring hormone replacement therapy (HRT) who have undergone hysterectomy. However, the cardiovascular effects of the progestogens used with oestrogen in the much larger number of women who have not undergone hysterectomy are unknown. Some widely used progestogens ha...

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Postmenopausal hormone replacement therapy and cardiovascular disease.

Cardiovascular disease is the leading cause of mortality in postmenopausal women in developed countries. A possible cardioprotective role of hormone replacement therapy (HRT) is suggested by epidemiologic studies of HRT and reduced risk of coronary heart disease, as well as by randomized trials of HRT and lipid subfractions. Estrogen has beneficial effects on the lipid profile, raising high-den...

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[Cardiovascular disease and hormone replacement therapy].

In Canada, cardiovascular disease (CVD) is the leading cause of mortality. In 1990, CVD killed 36,266 Canadian women. This represents 41 percent of deaths in women and is greater than all deaths due to cancer.' On average, Canadian women outlive men by seven years. During this period, CVD is second only to joint and bone dise'ase in limiting activities and reducing the autonomy of these women.2...

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[Menopausal hormone therapy and cardiovascular disease].

Despite biologically plausible mechanisms for cardiac protection and compelling evidence from observational studies suggesting that menopausal hormone therapy confers cardiovascular benefit, results of well-designed and conducted randomized clinical trials in healthy women and in women with established coronary heart disease displayed that menopausal hormone therapy failed to prevent clinical c...

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Postmenopausal Hormone Replacement Therapy and Cardiovascular Disease

Heart disease is the leading cause of death among postmenopausal American women. Although early observational studies suggested that hormone replacement therapy (HRT) might decrease these risks, prospective, experimental studies have not supported these results. With the recent release of these data in the media, clinicians are receiving numerous questions concerning HRT. This article reviews t...

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ژورنال

عنوان ژورنال: Taiwanese Journal of Obstetrics and Gynecology

سال: 2006

ISSN: 1028-4559

DOI: 10.1016/s1028-4559(09)60245-x